Low serological positivy in patients with histology compatible with celiac disease in Perú.
Objective: to study the frequency of positive serology for celiac
disease (CD) in patients with duodenal biopsies suggestive of
this disease. Material and methods: cross sectional study. We included
patients with duodenal biopsies histologically compatible with CD
and antigliadin, antiendomysial and IgA antitransglutaminase antibodies.
We defined a “case” of CD if there was a positive biopsy
and either antiendomisial or antitransglutaminase positive antibodies.
Results: thirty one patients were included in our study. Six
were antiendomysial positive and 5 antitransglutaminase positive
while the antigliadin was positive in 14 cases. Therefore, out of
31 patients only 10 had a serology compatible with CD and only
one had positive both antibodies, antiendomysial and antitransglutaminase.
Conclusions: a) we have found that most of the duodenal
biopsies compatible with CD are not diagnosed with positive serology;
and b) we found a low correlation between serological diagnostic
tests.
Authors: Arévalo, F.; Roe, E.; Arias-Stella Castillo, J.; Cárdenas, J.; Montes, P.; Monge, E.
Source: Rev. esp. enferm. dig
URL: http://hdl.handle.net/10757/314580
No hay comentarios:
Publicar un comentario