Prevalence of filariasis by Mansonella ozzardi and associated factors among 2 suburban communities of Iquitos, 2009

Introduction Three cases of M. ozzardi infection from 2 suburban communities in Iquitos, Peru, led to a suspicion of local transmission. The objective of the study was to determine the prevalence of filariasis by M. ozzardi and its associated factors among these communities. Materials and methods A cross-sectional study was performed, as well as an epidemiological survey and a thick smear blood test. Larvae and mosquitoes were collected. The adjusted OR (aOR) using multiple logistic regression was calculated. Results A total of 433 participants were enrolled; 58% were women. The prevalence of M. ozzardi was 1.4% and the associated factors included being a fisherman (aOR: 8.7; 95%CI: 1.1–76.0) and being on the Alto Nanay river (aOR: 11.2; 95%CI: 1.2–112.5). No significant evidence of simulidos or culicoides was found. Conclusion The low prevalence of M. ozzardi found suggests a foreign infection, probably derived from the Alto Nanay river.
Authors: Arróspide, Nancy; Reyna, Óscar; Montenegro Drogob, Juan José; Palominoa, Miriam; Lucero, Jorge; Villaseca, Pablo;León, Walter; Valenciaa, Pedro; Mayta Tristán, Percy
Source: Asociación Colombiana de Infectología (ACIN) (Infectio)

URL:  http://hdl.handle.net/10757/552949

Myocarditis and complicated dengue: a case report

Hemorragic dengue fever is a prevalent infection in many countries around the world. Myocarditis is a severe manifestation of dengue virus infection. With prompt intervention and an early diagnosis, the outcome of this condition can be improve. We report a adult patient with complicated dengue, myocarditis, cardiac and respiratory insufficiency with acute renal injury.
Authors: Pereda, María Gracia; López, Marianelly; Mariluz, Melissa
Source: Revista Chilena de Infectología (Rev Chilena Infectol.)

URL: http://hdl.handle.net/10757/552889

Contenido de sodio en la dieta diaria de niños de un albergue peruano

Sr. Editor:
En el 2008 se registró que la hipertensión es la causa del 45% de muertes por cardiopatías y del 51% de muertes por accidentes cardiovasculares en el mundo. Muchos factores pueden contribuir al aumento de las tasas de hipertensión, pero actualmente, el debate se ha centrado en el consumo de sal.2 La Organización Mundial de la Salud (OMS) ha recomendado la reducción del consumo de sal tanto en adultos a menos de 2 g de sodio por día, como en niños de 2 a 15 años, ajustándose de acuerdo a las necesidades de energía de los niños en comparación con las de los adultos.3
Autores: Trujillo Espino, Stefany; Paredes Aramburú, Jacqueline; Miranda Rodríguez, Camila; Bernabé Ortiz, Antonio
Fuente: Archivos argentinos de pediatría (Arch Argent Pediatr.)
URL: http://hdl.handle.net/10757/552698

La investigación científica es deficiente entre residentes de nefrología: el caso peruano

Introducción: La labor asistencial puede condicionar pobre dedicación a actividades de investigación científica en médicos que realizan la especialización de nefrología. Objetivo: Describir las prácticas de investigación científica entre los médicos residentes en nefrología y especialistas recién egresados en Perú. Material y métodos: Se realizó un estudio descriptivo de corte transversal sobre la totalidad de médicos residentes de nefrología de los dos últimos años y especialistas egresados de los dos últimos años a nivel nacional, mediante un cuestionario autoaplicado. Resultados: Se obtuvieron 40 respuestas, de las cuales el 50% correspondían a residentes. El 67.5% de los encuestados nunca realizó investigación durante la residencia. Ningún encuestado que haya realizado algún trabajo de investigación lo publicó. Casi todos consideraron a su sede hospitalaria como deficiente en investigación. Conclusión: La investigación científica entre residentes de nefrología en Perú es deficiente. Se requieren estrategias que la promuevan a este nivel.
Autores: Herrera Anazco, Percy; Mezones Holguin, Edward; Hernandez, Adrian V.
Fuente: Revista de nefrologia, dialisis y transplante (Rev. nefrol. dial. transpl.)
URL: http://hdl.handle.net/10757/552696

Acute Endovascular Reperfusion Therapy in Ischemic Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Background Randomized controlled trials (RCTs) of endovascular therapy for acute ischemic stroke have had inconsistent results. We evaluated the efficacy and safety of endovascular therapy in published RCTs. Methods We performed a systematic review of RCTs of endovascular therapy with thrombolytic or mechanical reperfusion compared with interventions without endovascular therapy. Primary outcome was the frequency of good functional outcome (modified Rankin scale (mRS) of 0-2 at 90 days) and secondary outcomes were mortality at 90 days and symptomatic intracranial hemorrhage (sICH). Random-effects meta-analysis was performed and the Cochrane risk of bias assessment was used to evaluate quality of evidence. Results Ten studies involving 1,612 subjects were included. Endovascular therapy was not significantly associated with good functional outcome (Relative Risk [RR] =1.17; 95% CI, 0.97 to 1.42; p=0.10 and Absolute Risk Difference [ARD] =7%; 95%CI -0.1% to 14%; p=0.05); heterogeneity was moderate among studies (I2=30%). Mortality was unchanged with endovascular therapy (RR=0.92; 95 % CI, 0.75 to 1.13; p=0.45) and there was no difference in sICH (RR=1.20; 95 % CI, 0.79 to 1.82; p=0.39). The quality of evidence was low for all outcomes and the recommendation is weak for the use of endovascular therapy as per GRADE methodology. Conclusions Intra-arterial therapy did not show significant increase in good outcomes and no changes in either mortality or sICH in patients with acute ischemic stroke. We need further RCTs with better design and quality to evaluate the true efficacy of endovascular therapy.
Authors: Osanai, Toshiya; Pasupuleti, Vinay; Deshpande, Abhishek; Thota, Priyaleela; Roman, Yuani; Hernandez, Adrian V.; Uchino, Ken
Source: PLoS ONE

URL:  http://hdl.handle.net/10757/552402