martes, 7 de julio de 2015

Importancia de la enseñanza de la medicina basada en evidencias.

Sr. Editor: Tal como se han reseñado en este espacio otros eventos de educación médica continua (1) y se ha resaltado la importancia de nuevos aspectos útiles para el médico en el campo de la atención individual y colectiva (2), consideramos pertinente brindar algunos alcances acerca de la Medicina Basada en Evidencias (MBE) en virtud a su relevancia como instrumento valioso en el quehacer profesional. Recientemente, la Facultad de Medicina de la Universidad Central de Venezuela (UCV) tuvo la oportunidad de organizar el Simposio Internacional Principios Básicos de la Medicina Basada en Evidencias (SIPBMBE), desarrollado el 12 de febrero de 2010 en el Auditorio Lorenzo Campins y Ballester, del Decanato de Medicina de la Ciudad Universitaria, desarrollado por el Departamento de Medicina Preventiva y Social de la Escuela de Medicina Luis Razetti de esa casa superior de estudios.
Autores: Rodríguez Morales, Alfonso J.Mezones Holguin, EdwardTolentino Silva, MarcusPuebla, SergioOrellana, Juan J.;Cárcamo, DanielNunes da Silva, EvertonRisquez Parra, AlejandroEchezuria Marval, LuisMayta Tristán, Percy
Fuente: Gac Méd Caracas
URL: http://hdl.handle.net/10757/314583

Bibliometrics: The Leiden Manifesto for research metrics

Data are increasingly used to govern science. Research evaluations that were once bespoke and performed by peers are now routine and reliant on metrics1. The problem is that evaluation is now led by the data rather than by judgement. Metrics have proliferated: usually well intentioned, not always well informed, often ill applied. We risk damaging the system with the very tools designed to improve it, as evaluation is increasingly implemented by organizations without knowledge of, or advice on, good practice and interpretation.
Before 2000, there was the Science Citation Index on CD-ROM from the Institute for Scientific Information (ISI), used by experts for specialist analyses. In 2002, Thomson Reuters launched an integrated web platform, making the Web of Science database widely accessible. Competing citation indices were created: Elsevier's Scopus (released in 2004) and Google Scholar (beta version released in 2004). Web-based tools to easily compare institutional research productivity and impact were introduced, such as InCites (using the Web of Science) and SciVal (using Scopus), as well as software to analyse individual citation profiles using Google Scholar (Publish or Perish, released in 2007).
Authors: Diana Hicks, Paul Wouters, Ludo Waltman, Sarah de Rijcke& Ismael Rafols
Source: Nature
URL: Full text

lunes, 6 de julio de 2015

Characteristics of gastroduodenal ulcers in patients with negative biopsies for Helicobacter pylori.

Objetives. To evaluate the clinical, epidemiological and endoscopic characteristics of the Helicobacter pylori (Hp) negative peptic ulcer disease. Methods. In this cross sectional study we included 651 patients diagnosed of peptic ulcer disease between January 2000 and December 2005. The diagnosis of Hp infection was established by histology. Clinical and epidemiological characteristics of patients with and without Hp infection were compared. Results. Males prevailed (69%). Hp negative ulcers were older (57,73 +/- 19,44 years old vs 50,26 +/- 18, 64 years old, P < 0.001). Clinical characteristics did not differ among both groups. Duodenal ulcer prevailed in Hp positive patients (56,5%) and gastric ulcer in Hp negative patients (53,5%). Multiple ulcers and intestinal metaplasia were more frequently found in Hp negative cases [9.3% vs 4.5 % (P = 0,015) and 34.5% vs 22.1% (P = 0,001), respectively]. Conclusion. Hp negative peptic ulcer disease is found in older patients, with a higher frequency of gastric ulcers, multiple lesions and intestinal metaplasia.
Authors: Montes Teves, PedroSalazar Ventura, SoniaMonge Salgado, Eduardo
Source: Acta Gastroenterol Latinoam

URL: http://hdl.handle.net/10757/314561

Low serological positivy in patients with histology compatible with celiac disease in Perú.

Objective: to study the frequency of positive serology for celiac disease (CD) in patients with duodenal biopsies suggestive of this disease. Material and methods: cross sectional study. We included patients with duodenal biopsies histologically compatible with CD and antigliadin, antiendomysial and IgA antitransglutaminase antibodies. We defined a “case” of CD if there was a positive biopsy and either antiendomisial or antitransglutaminase positive antibodies. Results: thirty one patients were included in our study. Six were antiendomysial positive and 5 antitransglutaminase positive while the antigliadin was positive in 14 cases. Therefore, out of 31 patients only 10 had a serology compatible with CD and only one had positive both antibodies, antiendomysial and antitransglutaminase. Conclusions: a) we have found that most of the duodenal biopsies compatible with CD are not diagnosed with positive serology; and b) we found a low correlation between serological diagnostic tests.
Authors: Arévalo, F.Roe, E.Arias-Stella Castillo, J.Cárdenas, J.Montes, P.Monge, E.
Source: Rev. esp. enferm. dig

URL: http://hdl.handle.net/10757/314580

Low publication of the papers presented at the Congresses of Gastroenterology Society of Peru 1998-2008.

OBJECTIVES: To determine the proportion of abstracts presented at the Congreso Peruano de Gastroenterología (the major Peruvian gastroenterological scientific meeting), that had been published in scientific journals, the date of publication and its associated factors. MATERIALS & METHODS: Longitudinal retrospective and analytic study; the publication rate of all the abstracts presented in the biennial Congreso Peruano de Gastroenterología between 1998 and 2008 was assessed. Google Scholar engine was used. The searching strategy performed included: (“Study location” AND “population studied” AND “main outcome”) AND (autor:First OR autor:Second OR autor:Last). Logistic regression was used, considering p<0.05 statistically significant. RESULTS: Publication rate was 8.2% (34/217), statistically significant differences were found among meeting years (p<0.001). There were also differences between study design, objectives (more in analytic studies) and measurement (more in longitudinal studies)(p<0.001). 82.4% were published in the Revista de Gastroenterología del Perú. The median time for publication was 10.8±10.4 months; this variable and the meeting year, study type, journal of publication or accordance between the abstract and publication characteristics showed no statistical differences. The mean authors’ number was 5.02±2.4; analytic studies have less authors than the descriptive ones (3.6 vs 6.1; p=0.012) CONCLUSION: The Congreso Peruano de Gastroenterología presents a low publication rate of the abstracts presented, which can be used as a quality indicator of the abstracts and the reviewing process.
Authors: Pereyra Elías, ReneéNg-Sueng, Luis FernandoToro-Polo, Luis MiguelNizama Vía, AyarPiscoya, Alejandro;Mayta Tristán, Percy
Source: Rev. gastroenterol. Perú

URL: http://hdl.handle.net/10757/314559