jueves, 7 de abril de 2016

Síntomas crónicos tras episodio de dengue, una necesidad de investigación

Carta al editor.




Fecha de publicación: Mar-2016



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Intimate partner violence is associated with stress-related sleep disturbance and poor sleep quality during early pregnancy

Objectives To examine the associations of Intimate partner violence (IPV) with stress-related sleep disturbance (measured using the Ford Insomnia Response to Stress Test [FIRST]) and poor sleep quality (measured using the Pittsburgh Sleep Quality Index [PSQI]) during early pregnancy. Methods This cross-sectional study included 634 pregnant Peruvian women. In-person interviews were conducted in early pregnancy to collect information regarding IPV history, and sleep traits. Adjusted odds ratios (aOR) and 95% confidence intervals (95%CIs) were calculated using logistic regression procedures. Results Lifetime IPV was associated with a 1.54-fold increased odds of stress-related sleep disturbance (95% CI: 1.08–2.17) and a 1.93-fold increased odds of poor sleep quality (95% CI: 1.33–2.81). Compared with women experiencing no IPV during lifetime, the aOR (95% CI) for stress-related sleep disturbance associated with each type of IPV were: physical abuse only 1.24 (95% CI: 0.84–1.83), sexual abuse only 3.44 (95%CI: 1.07–11.05), and physical and sexual abuse 2.51 (95% CI: 1.27–4.96). The corresponding aORs (95% CI) for poor sleep quality were: 1.72 (95% CI: 1.13–2.61), 2.82 (95% CI: 0.99–8.03), and 2.50 (95% CI: 1.30–4.81), respectively. Women reporting any IPV in the year prior to pregnancy had increased odds of stress-related sleep disturbance (aOR = 2.07; 95% CI: 1.17–3.67) and poor sleep quality (aOR = 2.27; 95% CI: 1.30–3.97) during pregnancy. Conclusion Lifetime and prevalent IPV exposures are associated with stress-related sleep disturbance and poor sleep quality during pregnancy. Our findings suggest that sleep disturbances may be important mechanisms that underlie the lasting adverse effects of IPV on maternal and perinatal health.


EditorialPLoS ONE
Fecha de publicación: Mar-2016

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miércoles, 6 de abril de 2016

El IGV en los flujos de caja

En el presente artículo se explica al lector, la manera en la que el manejo del Impuesto General a las Ventas puede impactar en la liquidez de un proyecto, realizando el cálculo respectivo de las operaciones de la empresa.

Editorial: Gaceta JurÍdica


Fecha de publicación: Enero 2012


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Nefropatía por poliomavirus en un paciente inmunosuprimido por trasplante renal secundario a la enfermedad de arteritis de Takayasu

Polyomavirus nephropathy is a disease that predominates in renal transplant patients due to the immunosuppressive treatment for the maintenance of the renal graft. The current prevalence of this disease ranges between 1-14%. The suspicion of the disease comes from the presence of decoy cells in urine samples and the gold standard for the diagnosis is the presence of viral inclusions in the renal biopsy. In this case report, we describe a patient with a renal transplant secondary to Takayasu arteritis who presented renal failure evidenced by progressive elevation of serum creatinine. The renal biopsy showed viral inclusions, confirming the diagnosis.




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martes, 5 de abril de 2016

The fecal virome of South and Central American children with diarrhea includes small circular DNA viral genomes of unknown origin

Viral metagenomics of feces collected from 58 Peruvian children with unexplained diarrhea revealed several small circular ssDNA genomes. Two genomes related to sequences previously reported in feces from chimpanzees and other mammals and recently named smacoviruses were characterized and then detected by PCR in 1.7 % (1/58) and 19 % (11/58) of diarrheal samples, respectively. Another three genomes from a distinct small circular ssDNA viral group provisionally called pecoviruses encoded Cap and Rep proteins with <35 % identity to those in related genomes reported in human, seal, porcine and dromedary feces. Pecovirus DNA was detected in 15.5 % (9/58), 5.9 % (3/51) and 3 % (3/100) of fecal samples from unexplained diarrhea in Peru, Nicaragua and Chile, respectively. Feces containing these ssDNA genomes also contained known human enteric viral pathogens. The cellular origins of these circular ssDNA viruses, whether human cells, ingested plants, animals or fungal foods, or residents of the gut microbiome, are currently unknown.




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