Objective: To examine the independent and joint relationships of poor subjective sleep quality and antepartum
depression with suicidal ideation among pregnant women.
Methods: A cross-sectional study was conducted among 641 pregnant women attending prenatal care clinics in
Lima, Peru. Antepartumdepression and suicidal ideationwere assessed using the Patient Health Questionnaire-9
scale. Antepartumsubjective sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Logistic
regression procedures were performed to estimate odds ratios (aOR) and 95% confidence intervals (95% CI) adjusted
for confounders.
Results: Overall, the prevalence of suicidal ideation in this cohort was 16.8% and poor subjective sleep qualitywas
more common among women endorsing suicidal ideation as compared to their counterpartswho did not (47.2%
vs. 24.8%, Pb.001). After adjustment for confounders including maternal depression, poor subjective sleep quality
(defined using the recommended criteria of PSQI global score of N5 vs. ≤5) was associated with a 1.7-fold increased
odds of suicidal ideation (aOR=1.67; 95% CI 1.02–2.71). When assessed as a continuous variable, each
1-unit increase in the global PSQI score resulted in an 18% increase in odds for suicidal ideation, even after
adjusting for depression (aOR=1.18; 95% CI 1.08–1.28). Women with both poor subjective sleep quality and depression
had a 3.5-fold increased odds of suicidal ideation (aOR=3.48; 95% CI 1.96–6.18) as compared with those
who had neither risk factor.
Conclusion: Poor subjective sleep quality was associated with increased odds of suicidal ideation. Replication of
these findings may promote investments in studies designed to examine the efficacy of sleep-focused interventions
to treat pregnant women with sleep disorders and suicidal ideation.
Author(s): Gelaye, Bizu; Barrios, Yasmin V.; Zhong, Qiu-Yue; Rondon, Marta B.; Borba, Christina P.C.; Sánchez, Sixto E.; Henderson, David C.; Williams, Michelle A.
Source: General Hospital Psychiatry (Gen
Hosp Psychiatry)
URL: http://hdl.handle.net/10757/555873
Producción académica de de la Universidad Peruana de Ciencias Aplicadas - UPC
jueves, 19 de noviembre de 2015
Research courses’ characteristics in Peruvian medical schools
Aim: To evaluate the research courses’ characteristics and the scientific output of
its teachers within Peruvian medical schools.
Methods: A cross-sectional descriptive study was performed, using data from
the medical schools existing in Peru in 2011. The research courses’ syllabi and its
teachers were evaluated. The number of courses, its teachers and the scientific
output of them were assessed. Results: Schools had a median of 5.5 [range 2 to 18] credits of research courses,
and 1.75% [0.6 to 6.3] was the median of percentages of total credits. In 18/32
(56%) schools existed at least one course requiring the student to present a final
inform, and only one school entailed the students to publish the courses’ products
in scientific journals. Furthermore, only five (16%) schools employed at least one
instructor that had ever published at least one original article as the corresponding
author in a Scopus-indexed journal.
Conclusion: Peruvian medical schools’ research courses do not include the
publication process as a targeted skill and its teachers have a poor scientific output.
Author(s): Taype Rondán, Á; Huaccho Rojas, J.; Pereyra Elías, R.; Mejia, C. R; Mayta Tristán, Percy
Source: Archivos de Medicina
URL: http://hdl.handle.net/10757/555579
Author(s): Taype Rondán, Á; Huaccho Rojas, J.; Pereyra Elías, R.; Mejia, C. R; Mayta Tristán, Percy
Source: Archivos de Medicina
URL: http://hdl.handle.net/10757/555579
Reducing salt in bread: a quasi-experimental feasibility study in a bakery in Lima, Peru
Objectives: To explore salt content in bread and to evaluate the feasibility of
reducing salt contained in ‘pan francés’ bread.
Design: The study had two phases. Phase 1, an exploratory phase, involved the
estimation of salt contained in bread as well as a triangle taste test to establish the
amount of salt to be reduced in ‘pan francés’ bread without detection by
consumers. In Phase 2, a quasi-experimental, pre–post intervention study assessed
the effects of the introduction of low-salt bread on bakery sales.
Setting: A municipal bakery in Miraflores, Lima, Peru.
Subjects: Sixty-five clients of the bakery in Phase 1 of the study; sales to usual
costumers in Phase 2.
Results: On average, there was 1·25 g of salt per 100 g of bread. Sixty-five
consumers were enrolled in the triangle taste test: fifty-four (83·1 %) females, mean
age 58·9 (SD 13·7) years. Based on taste, bread samples prepared with salt
reductions of 10 % (P = 0·82) and 20 % (P =0·37) were not discernible from regular
bread. The introduction of bread with 20 % of salt reduction, which contained 1 g
of salt per 100 g of bread, did not change sales of ‘pan francés’ (P=0·70) or other
types of bread (P =0·36). Results were consistent when using different statistical
techniques.
Conclusions: The introduction of bread with a 20 % reduction in salt is feasible
without affecting taste or bakery sales. Results suggest that these interventions are
easily implementable, with the potential to contribute to larger sodium reduction
strategies impacting the population’s cardiovascular health.
Author(s): Saavedra Garcia, Lorena; Sosa Zevallos, Vanessa; Diez Canseco, Francisco
Source: Public Health Nutrition (Public Health Nutrition)
URL: http://hdl.handle.net/10757/555477
Author(s): Saavedra Garcia, Lorena; Sosa Zevallos, Vanessa; Diez Canseco, Francisco
Source: Public Health Nutrition (Public Health Nutrition)
URL: http://hdl.handle.net/10757/555477
An unidentified cluster of infection in the Peruvian Amazon region
Introduction: Bartonella bacilliformis is the etiological agent of Carrion’s disease, which is a neglected disease linked to people in low-socioeconomic populations in Andean valleys. An outbreak of B. bacilliformis was reported in a rural area of the Peruvian Amazon region. The aim of this study was to characterize this outbreak using molecular techniques.
Methodology: Fifty-three blood samples from patients diagnosed with Carrion’s disease were analyzed by molecular tools, using both a Bartonella-specific polymerase chain reaction (PCR) and an universal PCR, both based on 16S rRNA gene amplification. Additional water samples from the area were also analyzed.
Results: Unexpectedly, the samples were positive only when the universal PCR was used. Although environmental contamination cannot be ruled out, the results showed that Sphingomonas faeni was the possible causative agent of this outbreak, and that water was the most feasible infection source.
Conclusions: Diagnosis by clinical criteria or microscopy may lead to misdiagnosis. There is a need to include molecular tools in the routine diagnosis of febrile syndromes, including Carrion’s disease.
Author(s): Cornejo Tapia, Ángela; Gomes, Cláudia; Suárez Ognio, Luis; Martínez Puchol, Sandra; Bustamante, Pershing; Pons, Maria J.; Ruiz, Joaquim; Del Valle Mendoza, Juana
Source: The Journal of Infection in Developing Countries (J Infect Dev Ctries.)
URL: http://hdl.handle.net/10757/555445
Author(s): Cornejo Tapia, Ángela; Gomes, Cláudia; Suárez Ognio, Luis; Martínez Puchol, Sandra; Bustamante, Pershing; Pons, Maria J.; Ruiz, Joaquim; Del Valle Mendoza, Juana
Source: The Journal of Infection in Developing Countries (J Infect Dev Ctries.)
URL: http://hdl.handle.net/10757/555445
Atypical presentation of Gorham-Stout syndrome. Case report
Gorham-Stout syndrome is an extremely rare pathology, of unknown etiology. It is characterized by proliferation of vascular channels that causes destruction and reabsorption of the bone matrix. We present a nine year-old male patient with an acute episode characterized by fever, chest pain, respiratory distress and dyspnea. The patient was submitted to computed tomography scan and a biopsy. The findings in the biopsy were multiple lytic lesions, osteolysis, and a mediastinal lymphangioma (lymphangiomatosis). The diagnosis was Gorham-Stout syndrome with atypical presentation
Author(s): González Luna, Alejandro; Nuñez Pizarro, Jorge Luis; Rodríguez Echegaray, Clodo Iván
Source: Archivos argentinos de pediatría (Arch. argent. pediatr.)
URL: http://hdl.handle.net/10757/555429
Author(s): González Luna, Alejandro; Nuñez Pizarro, Jorge Luis; Rodríguez Echegaray, Clodo Iván
Source: Archivos argentinos de pediatría (Arch. argent. pediatr.)
URL: http://hdl.handle.net/10757/555429
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