Atypical presentation of Gorham-Stout syndrome. Case report

Gorham-Stout syndrome is an extremely rare pathology, of unknown etiology. It is characterized by proliferation of vascular channels that causes destruction and reabsorption of the bone matrix. We present a nine year-old male patient with an acute episode characterized by fever, chest pain, respiratory distress and dyspnea. The patient was submitted to computed tomography scan and a biopsy. The findings in the biopsy were multiple lytic lesions, osteolysis, and a mediastinal lymphangioma (lymphangiomatosis). The diagnosis was Gorham-Stout syndrome with atypical presentation

Author(s): González Luna, Alejandro; Nuñez Pizarro, Jorge Luis; Rodríguez Echegaray, Clodo Iván
Source:  Archivos argentinos de pediatría (Arch. argent. pediatr.)

URL: http://hdl.handle.net/10757/555429

Characterization of two Achromobacter xylosoxidans isolates from patients with pertussis-like symptoms

Objective: To characterize two Achromobacter xylosoxidans recovered from 2 patients diagnosed with pertussis during a Bordetella pertussis surveillance program. Methods: Nasopharyngeal swabs from 2 children under 1 year of age with clinical suspicion of pertussis were analyzed by culture and PCR. Results: Two Achromobacter xylosoxidans A8, closely related to Bordetella spp. were recovered from 2 patients diagnosed of pertussis, both carrying the ptxA gene and IS418 the pertussis toxin encoding gene. Subsequently, antibiotic susceptibility was evaluated by disk-diffusion method and by PCR. Conclusions: Although more detailed studies are needed, the present data highlight the possibility that Achromobacter xylosoxidans, closely related Bordetella pertussis microorganisms and not covered under the vaccine umbrella, might also result in cases of whooping cough. Thereby further surveillance is necessary to determine the extension and relevance of their pathogenic role in order to discriminate their real public health implication.

Author(s): Pons, Maria J.; Gomes, Cl觃udia; Bada, Carlos; Reyes, Isabel; Del Valle Mendoza, Juana; Ruiz, Joaquim
Source:  Asian Pacific Journal of Tropical Medicine (Asian Pacific Journal of Tropical Medicine)

URL: http://hdl.handle.net/10757/554305

Nephrology: is a medical specialty unattractive to Peruvian doctors?

Although the National Committee of Medical Residency (CONAREME) has increased the number of nephrology residency positions in Peru, the increase has not been proportional to the number of applicants. This is worrisome in an environment lacking of nephrologists, like our country. The Peruvian Society of Nephrology (SPN) should take the measures to make this specialty more attractive to Peruvian physicians.

Author(s): Herrera Añazco, Percy; Mezones Holguin, Edward; Hernandez, Adrian V.
Source:  Jornal Brasileiro de Nefrologia (J. Bras. Nefrol)

URL: http://hdl.handle.net/10757/554221

Factors associated with poor sleep quality among patients with chronic kidney diseases in hemodialysis

Introduction and objectives Sleep disorders are one of the most common comorbidities among patients on hemodialysis. The aims of this study were to determine the prevalence of poor sleep quality as well as to establish potential factors associated with poor sleep quality. Materials and methods A cross-sectional study was performed enrolling patients with chronic kidney disease on hemodialysis. The outcome was sleep quality evaluated using the Pittsburgh Scale, whereas the exposure variables were time on hemodialysis, history of type-2 diabetes and hypertension, depressive symptoms, anemia, and uremia. We used Poisson regression model to determine the association of interest, reporting prevalence ratios (PR) and 95% confidence intervals (95%CI). Results A total of 450 patients were enrolled, 259 (57.5%) were male, aged from 18 to 97 years. The prevalence of poor sleep quality was 79.3% (95%CI: 75.6%–83.1%). Poor sleep quality was associated with depressive symptoms (PR = 1.28; 95%CI: 1.17-1.39), anemia (PR = 1.18; 95%CI: 1.04-1.34) and uremia (PR = 1.26; 95%CI: 1.17-1.36) after controlling for potential confounders. Conclusions The presence of depressive symptoms, anemia and uremia were positively associated with poor sleep quality among patients with chronic kidney disease on hemodialysis. A great proportion of this population had poor sleep quality. Strategies are needed to improve sleep quality in these patients.

Author(s): Peña Martínez, Bruce; Navarro, Veronica; Oshiro, Harumi; Bernabe Ortiz, Antonio
Source:  Elsevier B.V.

URL: Dialisis y Traspante (Dial Traspl)

Prevalence of filariasis by Mansonella ozzardi and associated factors among 2 suburban communities of Iquitos, 2009

Introduction Three cases of M. ozzardi infection from 2 suburban communities in Iquitos, Peru, led to a suspicion of local transmission. The objective of the study was to determine the prevalence of filariasis by M. ozzardi and its associated factors among these communities. Materials and methods A cross-sectional study was performed, as well as an epidemiological survey and a thick smear blood test. Larvae and mosquitoes were collected. The adjusted OR (aOR) using multiple logistic regression was calculated. Results A total of 433 participants were enrolled; 58% were women. The prevalence of M. ozzardi was 1.4% and the associated factors included being a fisherman (aOR: 8.7; 95%CI: 1.1–76.0) and being on the Alto Nanay river (aOR: 11.2; 95%CI: 1.2–112.5). No significant evidence of simulidos or culicoides was found. Conclusion The low prevalence of M. ozzardi found suggests a foreign infection, probably derived from the Alto Nanay river

Author(s): Arróspide, Nancy; Reyna, Óscar; Montenegro Drogob, Juan José; Palominoa, Miriam; Lucero, Jorge; Villaseca, Pablo; León, Walter; Valenciaa, Pedro; Mayta Tristán, Percy
Source: Asociación Colombiana de Infectología (ACIN) (Infectio)

URL: http://hdl.handle.net/10757/552949