Coinfection of dengue and leptospirosis in a girl from the Peruvian Amazon

We report the case of a 10 year old girl, born and raised in the city of Iquitos in Peru who presented with headache, fever, chills, musculoskeletal pain, mild epigastric pain, epistaxis and hematemesis. On physical examination, the patient was afebrile and in good general condition. Serological tests confirmed infection of dengue and leptospirosis. The patient received intravenous hydration with sodium chloride 0.9% and penicillin G sodium, achieving a favorable clinical course such that she was discharged a few days after admission to the hospital. Although these diseases are common in the Peruvian Amazon, the simultaneous presence of both in the pediatric population is little documented; therefore, a good clinical history and laboratory tests are important for diagnosis and treatment.
Authors: Núñez Garbín, Alexandra; Espinoza Figueroa, Jossué; Sihuincha Maldonado, Moisés; Suárez Ognio, Luis
Source: Revista Peruana de Medicina Experimental y Salud Pública (Rev Peru Med Exp Salud Publica)

URL: http://hdl.handle.net/10757/348595

Medición y magnitud del bullying en Perú

Sr. Editor. El bullying es un problema de salud pública que incluye a tres actores: la víctima, el victimario/ agresor y el observador, y es un hecho que está cada vez más presente en nuestra sociedad, pues se discute sus implicancias en escenarios de salud, educación y hasta en la prensa. Sin embargo, la información científica disponible sobre la magnitud del bullying en el Perú (Tabla 1) muestra prevalencias bastante elevadas y hasta alarmantes, por lo que es válido preguntarse si es que el bullying en el Perú se está midiendo de manera correcta.
Autores: Cobián Lezama, Carla; Nizama-Vía, Ayar; Ramos Aliaga, David; Mayta Tristán, Percy
Fuente: Revista Peruana de Medicina Experimental y Salud Pública (Rev Peru Med Exp Salud Publica)
URL: http://hdl.handle.net/10757/348574

Cuestionarios de calidad de vida en cáncer de próstata quirúrgico: University of California-Los Angeles-Prostate Cancer Index (UCLA-PCI) vs. Expanded Prostate Cancer Index (EPIC) vs. Cuestionario Calidad de Vida en Pacientes con Cáncer de Próstata (CAVIPRES)

Sr. Editor: Hemos leído con interés el artículo «Calidad de vida en pacientes con cáncer de próstata, operados de prostatectomía radical laparoscópica», desarrollado por Sierra-Guerra et al., donde se describe el impacto del cáncer de próstata en la calidad de vida de los pacientes afectados1. Al respecto, existen varios instrumentos para evaluar este aspecto, siendo los más importantes el University of California-Los Angeles Prostate Cancer Index (UCLA-PCI), el Expanded Prostate Cancer Index (EPIC) y el Cuestionario Espanol ˜ de Calidad de Vida en Pacientes con Cáncer de Próstata (CAVIPRES). El UCLA-PCI fue el primer instrumento desarrollado para este fin, fue hecho en Estados Unidos y luego adaptado y validado al espanol ˜ en varios estudios latinamericanos2. El EPIC es una versión extendida del UCLA y, a diferencia de este, también puede ser utilizado en pacientes con estadios clínicos avanzados. Ambos son enfermedad-específicos y, por lo tanto, más sensibles que los generales3.
Autores: Leon-Miranda, B.; Roca Quicaño, Ricardo; Chavez Porras, A.
Fuente Revista Mexicana de Urología (Rev Mex Urol)
URL: http://hdl.handle.net/10757/348556

Physical performance of older adults living in rural areas at sea level and at high altitude in Peru

Introduction: Living at high altitudes requires the inhabitants to adapt biologically and socially to the environment. The objective of this study was to determine the difference in physical performance (PP) in rural populations at sea level and at high altitude. Material and methods: A cross-sectional study was conducted in rural communities in Ancash, Peru, located at 3.345 meters above sea level (m.a.s.l.) and also in communities located in coastal areas at 6 m.a.s.l. PP was measured by the Short Physical Performance Battery (SPPB) and other associated factors. Adjusted prevalence ratios (aPR) were calculated. Results: A total of 130 older adults were assessed in the high altitude communities and 129 on the coast. The median age was 71.4 years, and 55.6 % were female. Low physical performance (SPPB ≤ 6) was 10.0 % at high altitude and 19.4 % on the coast (p <0.05). Factors associated with low physical performance were residing at the coast (aPR: 2.10, 95 % CI 1.02 to 4.33), self-reported poor health (aPR: 2.48, 95 % CI 1.21 -5.08), hypertension (aPR: 1.73, 95 % CI 1.01 to 2.98), and age (aPR: 1.04, 95 % CI 1.01 to 1.07), while being a farmer (aPR: 0.49, 95 % CI 0.25 to 0.97), and being independent (aPR: 0.37, 95 % CI 0,20-, 072) were found to be protective factors. It was also found that the inhabitants of the coast have a mean of 0.86 points lower total SPPB than the high altitude ones (p =0.004). Conclusions: There is an association between altitude of residence and PP in older adults. The prevalence of a low PP in older adults in rural areas at sea level is twice as high compared to those living in high altitude rural communities
Authors: Estela Ayamamania, David; Espinoza Figueroa, Jossué; Columbus Morales, Mauricio; Runzer Colmenares, Fernando;Parodi, José F.; Mayta Tristán, Percy
Source: Revista Española de Geriatría y Gerontología (Rev Esp Geriatr Gerontol)

URL: http://hdl.handle.net/10757/348544

Effect of vitamin D supplementation during pregnancy on maternal and neonatal outcomes: a systematic review and meta-analysis of randomized controlled trials

Objective: To assess the effects of vitamin D supplementation during pregnancy on obstetric outcomes and birth variables. Design: Systematic review and meta-analysis of randomized controlled trials (RCTs). Setting: Not applicable. Patient(s): Pregnant women and neonates. Intervention(s): PubMed and 5 other research databases were searched through March 2014 for RCTs evaluating vitamin D supplementation calcium/vitamins/ferrous sulfate vs. a control (placebo or active) during pregnancy. Main Outcome Measure(s): Measures were: circulating 25-hydroxyvitamin D [25(OH)D] levels, preeclampsia, gestational diabetes mellitus (GDM), small for gestational age (SGA), low birth weight, preterm birth, birth weight, birth length, cesarean section. Mantel-Haenszel fixed-effects models were used, owing to expected scarcity of outcomes. Effects were reported as relative risks and their 95% confidence intervals (CIs). Result(s): Thirteen RCTs (n ¼ 2,299) were selected. Circulating 25(OH)D levels were significantly higher at term, compared with the control group (mean difference: 66.5 nmol/L, 95% CI 66.2–66.7). Birth weight and birth length were significantly greater for neonates in the vitamin D group; mean difference: 107.6 g (95% CI 59.9–155.3 g) and 0.3 cm (95% CI 0.10–0.41 cm), respectively. Incidence of preeclampsia, GDM, SGA, low birth weight, preterm birth, and cesarean section were not influenced by vitamin D supplementation. Across RCTs, the doses and types of vitamin D supplements, gestational age at first administration, and outcomes were heterogeneous. Conclusion(s): Vitamin D supplementation during pregnancy was associated with increased circulating 25(OH)D levels, birth weight, and birth length, and was not associated with other maternal and neonatal outcomes. Larger, better-designed RCTs evaluating clinically relevant outcomes are necessary to reach a definitive conclusion. (Fertil Steril 2015;-:-–-. 2015 by American Society for Reproductive Medicine.)
Authors: Perez López, Faustino R.; Pasupuleti, Vinay; Mezones Holguin, Edward; Benites Zapata, Vicente A.; Thota, Priyaleela;Deshpande, Abhishek; Hernandez, Adrian V.
Source: Fertility and Sterility

URL: http://hdl.handle.net/10757/347325